FSH beta Recombinant Rabbit mAb
- 产品详情
- 实验流程
Application
| WB, IHC-P, IHC-F, IF, IP |
|---|---|
| Reactivity | Human |
| Predicted | Rabbit |
| Host | Rabbit |
| Clonality | Recombinant |
| Calculated MW | 15 KDa |
| Physical State | Liquid |
| Immunogen | A synthesized peptide derived from human FSH beta |
| Epitope Specificity | 30-84 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the glycoprotein hormones subunit beta family. |
| SUBUNIT | Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. |
| DISEASE | Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency (IFSHD) [MIM:229070]. Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
| Other Names | FSHB_HUMAN; FSHB; Follicle-stimulating hormone beta subunit (FSH-B | FSH-beta); Follitropin beta chain; FSHB_RABIT; follicle stimulating hormone subunit beta; follicle stimulating hormone, beta polypeptide; follitropin, beta chain |
|---|---|
| Dilution | WB=1:500-2000,IP=1:50-200,IHC-F=1:200-1000,IHC-P=1:200-1000,IF=1:200-1000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Name | FSH beta Recombinant Rabbit mAb |
| Function | Stimulates development of follicle and spermatogenesis in the reproductive organs. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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