癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
C1orf38 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q5TEJ8 |
| Other Accession | Q5TEJ8 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 72049 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human C1orf38 |
| Epitope Specificity | 1-100/643 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the themis family. |
| SUBUNIT | When phosphorylated, interacts with LYN. Interacts with VAV1 and GRB2 (By similarity). |
| Post-translational modifications | Phosphorylation at Tyr-632 is induced by LPS (By similarity). |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Gene ID | 9473 |
|---|---|
| Other Names | C1orf38; ICB-1; ICB1; THMS2_HUMAN; THEMIS2; Induced by contact to basement membrane 1 protein (Protein ICB-1); Thymocyte-expressed molecule involved in selection protein 2; thymocyte selection associated family member 2; chromosome 1 open reading frame 38; induced by contact to basement membrane 1 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | THEMIS2 (HGNC:16839) |
|---|---|
| Function | May constitute a control point in macrophage inflammatory response, promoting LPS-induced TLR4-mediated TNF production (PubMed:20644716). Determines the threshold for activation of B cells by low-affinity and low-avidity ligands via PLCG2 activation and its downstream pathways (By similarity). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q91YX0}. Cytoplasm {ECO:0000250|UniProtKB:Q91YX0} |
| Tissue Location | Expressed in different endometrial adenocarcinoma cell lines and various other cell lines apart from the prostate cell line LNCaP and the ovarian cancer cell line BG1 |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP96729
