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Klrb1c Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | P27814 |
| Other Accession | P27814 |
| Reactivity | Rat, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 25077 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from mouse CD161c/NK1.1 |
| Epitope Specificity | 101-200/223 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBUNIT | Homodimer; disulfide-linked. Interacts with tyrosine kinase LCK. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Enables identical protein binding activity and signaling receptor activity. Acts upstream of or within natural killer cell activation and positive regulation of natural killer cell mediated cytotoxicity. Located in external side of plasma membrane. Is integral component of plasma membrane. Is expressed in thymus primordium. Orthologous to human KLRB1 (killer cell lectin like receptor B1). [provided by Alliance of Genome Resources, Apr 2022] |
| Gene ID | 17059 |
|---|---|
| Other Names | CD161; Klrb1b; Ly-59; Ly55c; Ly59; NK-RP1; NK1.1; NKR-P1.9; NKRP1; NKRP140; Nk-1; Nk-1.2; Nk1; Nk1.2; Nkrp1b; Nkrp1c; ly-55c; NKR-P1A; Nkrp1a; KLRBC_MOUSE; Klrb1c; CD161 antigen-like family member C; Lymphocyte antigen 55c (Ly-55c); NKR-P1C; Natural killer cell surface protein P1-40 (NKR-P1 40); KLRB1_RAT; Klrb1; Immunoreceptor NKR-P1E; Killer cell lectin-like receptor subfamily B member 1G; Natural killer cell surface protein NKR-P1G; Natural killer lectin-like receptor 1E; Klrb1d; Klrb1g; Klrb6; Nkrp1e; Nkrp1g; CLEC5B; NKR; NKR-P1; hNKR-P1A; |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Klrb1c |
|---|---|
| Synonyms | Ly55c, Nkrp1c |
| Function | Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization and interferon-gamma production. |
| Cellular Location | Membrane; Single-pass type II membrane protein. |
| Tissue Location | Expressed in natural killer cells. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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