癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
GIPC3 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q8TF64 |
| Other Accession | Q8TF64 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 33982 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human GIPC3 |
| Epitope Specificity | 151-250/312 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the GIPC family. Contains 1 PDZ (DHR) domain. |
| DISEASE | Deafness, autosomal recessive, 15 (DFNB15) [MIM:601869]: A form of non-syndromic sensorineural hearing loss with prelingual onset. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Note=The disease is caused by mutations affecting the gene represented in this entry. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The protein encoded by this gene belongs to the GIPC family. Studies in mice suggest that this gene is required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion in the ear. Mutations in this gene are associated with autosomal recessive deafness. [provided by RefSeq, Dec 2011] |
| Gene ID | 126326 |
|---|---|
| Other Names | C19orf64; DFNB15; DFNB72; DFNB95; GIPC3_HUMAN; GIPC3; GIPC PDZ domain containing family member 3; chromosome 19 open reading frame 64; deafness, autosomal recessive 72; deafness, autosomal recessive 15; GIPC PDZ domain containing family, member 3 |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | GIPC3 |
|---|---|
| Synonyms | C19orf64 |
| Function | Required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion. |
| Tissue Location | Widely expressed in adult and fetal tissues. Highest levels are found in jejunum, lymph node, parietal lobe, fetal spleen and fetal thymus. Expressed in cervical, melanoma, chronic myelogenous and gastric cancer cell lines |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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