MFAP1 Rabbit pAb
- 产品详情
- 实验流程
Application
| WB |
|---|---|
| Primary Accession | P55081 |
| Other Accession | P55081 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 51958 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human MFAP1 |
| Epitope Specificity | 31-120/439 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the MFAP1 family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Microfibrils are an important component of the extracellular matrix of many tissues and can either associate with or without elastin. Several microfibril associated proteins (MFAPs) have been cloned, including MFAP1, MFAP3 and MFAP4. The MFAP1 and MFAP3 genes are localized near the fibrillin genes FBN1 and FBN2, respectively. Mutations in FBN1 are linked to Marfan syndrome. Mutations in FBN2 have been linked to congenital contractural arachnodactyly. This suggests roles for MFAP1 and MFAP3 in heritable diseases affecting microfibrils. Deletion of MFAP4 was found in 30 of 31 patients with Smith-Magenis syndrome (SMS), a clinically recognizable multiple congenital anomaly/mental retardation syndrome. |
| Gene ID | 4236 |
|---|---|
| Other Names | AMP; Mfap1a; 4432409M24Rik; Mfap1; Mfap1b; MFAP1_HUMAN; Spliceosome B complex protein MFAP1; MFAP1_MOUSE; microfibril associated protein 1; microfibrillar associated protein 1 |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | MFAP1 (HGNC:7032) |
|---|---|
| Function | Involved in pre-mRNA splicing as a component of the spliceosome. |
| Cellular Location | Nucleus. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Cat# AP96820
















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