癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
TBX22 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q8K402 |
| Other Accession | Q8K402 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 58498 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from mouse TBX22 |
| Epitope Specificity | 21-120/517 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Contains 1 T-box DNA-binding domain. |
| DISEASE | The disease is caused by mutations affecting the gene represented in this entry. Disease description:A congenital mouth abnormality characterized by fissure of the soft and/or hard palate, due to faulty fusion. Some patients also manifest ankyloglossia, a condition in which movements of the tongue are restricted. Complete ankyloglossia is due to fusion between the tongue and the floor of the mouth. Partial ankyloglossia is due to a short lingual frenum or one which is attached too near the tip of the tongue. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Gene ID | 245572 |
|---|---|
| Other Names | ABERS; CLPA; CPX; TBXX; dJ795G23.1; D230020M15Rik; Tbx 22; TBX22_HUMAN; TBX22; T-box protein 22; TBOX22; TBX22_MOUSE; T-box transcription factor 22; cleft palate and/or ankyloglossia; T-box 22 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Tbx22 |
|---|---|
| Function | Probable transcriptional regulator involved in developmental processes. This is major determinant crucial to palatogenesis. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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