癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
AKAP14 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | O35817 |
| Other Accession | O35817 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 55756 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from rat AKAP14 |
| Epitope Specificity | 81-180/502 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBUNIT | Binds to type II regulatory subunits (RII). |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene encodes a member of A-kinase anchoring proteins (AKAPs), a family of functionally related proteins that target protein kinase A to discrete locations within the cell. The human ortholog of this gene has been characterized. It is reported to be enriched in airway cilia and to regulate ciliary beat frequency by anchoring the protein kinase A holoenzyme near substrates in the axoneme. [provided by RefSeq, May 2013]. |
| Gene ID | 60332 |
|---|---|
| Other Names | AKA14_RAT; Akap14; AKAP-14; TAKAP-1.2; Testis-specific A-kinase-anchoring protein TAKAP-80; Takap80; AKA28_HUMAN; A-kinase anchor protein 28 kDa (AKAP 28); Protein kinase A-anchoring protein 14 (PRKA14); AKAP28; PRKA14; A-kinase anchoring protein 14; A kinase (PRKA) anchor protein 14 |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Akap14 |
|---|---|
| Synonyms | Takap80 |
| Function | Binds to type II regulatory subunits of protein kinase A and anchors/targets them. |
| Cellular Location | Cytoplasm. Note=In fibrous sheath from epididymal sperm |
| Tissue Location | Testis specific.. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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