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LTB4-R1/LTB4R Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Reactivity | Mouse |
| Predicted | Rat, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 39 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from mouse LTB4-R1/LTB4R |
| Epitope Specificity | 201-300/351 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the G-protein coupled receptor 1 family. |
| Post-translational modifications | Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Leukotriene B4 Receptor is a member of the GPCR family (subfamily:chemoattractant). It is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. It has been reported in blood, bone marrow, brain, heart, liver, and skeletal muscle. In addition, it has been shown to be highly expressed in leukocytes and lymphoid tissues such as spleen, thymus, and lymph node. ESTs have been isolated from B cell/lung/testis, breast, colon, eye, kidney, skin, spleen, testis, and tonsil libraries. |
| Other Names | BLT1; BLTR; CMKRL1; GPR16; LTB4R1; LTBR1; P2RY7; P2Y7; LT4R1_HUMAN; LTB4R; LTB4-R 1; LTB4-R1; Chemoattractant receptor-like 1; G-protein coupled receptor 16; P2Y purinoceptor 7 (P2Y7); BLT; leukotriene B4 receptor |
|---|---|
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Name | LTB4-R1/LTB4R Rabbit pAb |
| Function | Receptor for extracellular ATP, UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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