癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
GSG1L Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q6UXU4 |
| Other Accession | Q6UXU4 |
| Reactivity | Rat, Mouse |
| Predicted | Pig, Human, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 36774 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human GSG1L |
| Epitope Specificity | 1-100/331 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the GSG1 family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | GSG1L is a 331 amino acid multi-pass membrane protein belonging to the GSG1 family. Existing as four alternatively spliced isoforms, GSG1L is encoded by a gene located on human chromosome 16, which encodes over 900 genes, comprises nearly 3% of the human genome and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. A rare disorder known as Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. |
| Gene ID | 146395 |
|---|---|
| Other Names | PRO19651; C230098I05Rik; G630023A01Rik; Gm637; g1l; RGD1562278; GSG1L_HUMAN; GSG1L; GSG1-like protein; GSG1L_MOUSE; GSG1L_RAT; GSG1L_DANRE; GSG1 like |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | GSG1L |
|---|---|
| Function | As a component of the inner core of AMPAR complex, modifies AMPA receptor (AMPAR) gating. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Synapse |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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