癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
hnRNP H2 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | P55795 |
| Other Accession | P55795 |
| Reactivity | Mouse |
| Predicted | Rat, Pig, Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 49264 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human hnRNP H2 |
| Epitope Specificity | 101-200/449 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Contains 3 RRM (RNA recognition motif) domains. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed. [provided by RefSeq, Jan 2011] |
| Gene ID | 3188 |
|---|---|
| Other Names | FTP3; HNRPH'; HNRPH2; MRXSB; NRPH2; hnRNPH'; DXHXS1271E; Ftp-3; H'; HNRNP; HNRH2_HUMAN; HNRNPH2; hnRNP H2; Heterogeneous nuclear ribonucleoprotein H' (hnRNP H'); HNRH2_MOUSE; HNRH2_RAT; heterogeneous nuclear ribonucleoprotein H2; heterogeneous nuclear ribonucleoprotein H2 (H') |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | HNRNPH2 |
|---|---|
| Synonyms | FTP3, HNRPH2 |
| Function | This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG). |
| Cellular Location | Nucleus, nucleoplasm |
| Tissue Location | Expressed ubiquitously. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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