癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
IDI2 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q9BXS1 |
| Other Accession | Q9BXS1 |
| Reactivity | Mouse |
| Predicted | Human, Chicken |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 26753 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human IDI2 |
| Epitope Specificity | 1-100/227 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the IPP isomerase type 1 family. Contains 1 nudix hydrolase domain. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | IDI2 is a 227 amino acid protein that belongs to the IPP isomerase type 1 family. Localizing to the peroxisome, IDI2 is expressed in skeletal muscle and contains one nudix hydrolase domain. IDI2 utilizes magnesium as a cofactor and participates in isoprenoid biosythesis. IDI2 catalytically converts isopentenyl diphosphate (IPP) to its electrophilic isomer, dimethylallyl diphosphate (DMAPP), a substrate for subsequent reactions that synthesize farnesyl diphosphate and, ultimately, cholesterol. The gene encoding IDI2 maps to human chromosome 10p15.3. Segmental copy-number gains to the IDI2 gene may contribute to the pathogenesis of sporadic amyotrophic lateral sclerosis (SALS). SALS, also known as Lou Gehrig's disease, is a motor neuron disease characterized by neuron degeneration |
| Gene ID | 91734 |
|---|---|
| Other Names | IPPI2; 4833405L16Rik; RGD1559783; RGD1562352; IDI2_HUMAN; IDI2; Isopentenyl pyrophosphate isomerase 2 (IPP isomerase 2 | IPPI2); 5.3.3.2; Q4FZF0_MOUSE; isopentenyl-diphosphate delta isomerase 2 |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | IDI2 |
|---|---|
| Function | Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). |
| Cellular Location | Peroxisome. |
| Tissue Location | Muscle-specific expression. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
终于等到您。ABCEPTA（百远生物）抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息，您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问，联系：0512-88856768 tech-china@abcepta.com.
