癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
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MANBA Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | O00462 |
| Other Accession | O00462 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 100895 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human MANBA |
| Epitope Specificity | 601-700/879 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the glycosyl hydrolase 2 family. |
| DISEASE | Defects in MANBA are the cause of a mild disorder that affects peripheral and central nervous system myelin. Mannosidosis, beta A, lysosomal |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Gene ID | 4126 |
|---|---|
| Other Names | MANB1; MANBA_HUMAN; MANBA; Lysosomal beta A mannosidase; Mannanase (Mannase); 3.2.1.25; mannosidase beta; mannosidase, beta A, lysosomal; beta-mannosidase A |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | MANBA |
|---|---|
| Synonyms | MANB1 |
| Function | Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides. |
| Cellular Location | Lysosome. |
| Tissue Location | Ubiquitous. Detected in pancreas, kidney and placenta, ands at lower levels in liver, lung, brain, heart and muscle |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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