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P2Y10 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | O00398 |
| Other Accession | O00398 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 38774 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human P2Y10 |
| Epitope Specificity | 151-250/339 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the G-protein coupled receptor 1 family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Nucleotides are important extracellular signaling molecules that mediate several events, such as cell proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, designated P2X and P2Y. The P2Y receptor family are G protein-coupled receptors that mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C (PLC). To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. P2Y10 (purinergic receptor P2Y, G-protein coupled, 10), also known as P2RY10, is a 339 amino acid multi-pass membrane protein that is thought to act as a receptor for purines coupled to G-proteins. P2Y10 is found at low levels in blood leukocytes and is upregulated during promyelocytic cell differentiation. |
| Gene ID | 27334 |
|---|---|
| Other Names | LPS2; LYPSR2; P2Y10; 5830408N17Rik; P2Y10_HUMAN; P2RY10; P2Y-like receptor; P2Y10_MOUSE; P2Y receptor family member 10; purinergic receptor P2Y, G-protein coupled, 10; purinergic receptor P2Y10; lysophosphatidylserine receptor 2 |
| Dilution | WB=1:500-2000,Flow-Cyt=1 µg/Test |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | P2RY10 |
|---|---|
| Function | Putative receptor for purines coupled to G proteins. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | Weakly expressed in blood leukocytes. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP97098
