癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
AX2R Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q3ZCQ2 |
| Other Accession | Q3ZCQ2 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 21682 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human AX2R |
| Epitope Specificity | 30-90/193 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | ANXA2R (annexin-2 receptor), also known as AX2R or C5orf39, is a 193 amino acid protein that is widely expressed and may act as an annexin II receptor on marrow stromal cells to induce osteoclast formation. In addition, ANXA2R is highly expressed in lymphocytes and is also found in resting CD4+ and CD8+ T cells. The gene encoding ANXA2R maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
| Gene ID | 389289 |
|---|---|
| Other Names | AX2R; AXIIR; C5orf39; AX2R_HUMAN; ANXA2R; Annexin II receptor (AXIIR); annexin A2 receptor; chromosome 5 open reading frame 39 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ANXA2R |
|---|---|
| Synonyms | AX2R, C5orf39 |
| Function | May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation. |
| Tissue Location | Widely expressed. Highly expressed in lymphocytes. Expressed in both resting CD4(+) and CD8(+) T-cells |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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