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Epigen Rabbit pAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IHC-F, IF, E
Primary Accession Q6UW88
Other Accession Q6UW88
Predicted Rat, Human, Mouse, Dog, Horse, Sheep
Host Rabbit
Clonality Polyclonal
Calculated MW 17091 Da
Physical State Liquid
Immunogen KLH conjugated synthetic peptide derived from human Epigen
Epitope Specificity 51-130/154
Isotype IgG
Purity affinity purified by Protein A
Buffer 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SIMILARITY Contains 1 EGF-like domain.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence.
Additional Information
Gene ID 255324
Other Names ALGV3072; EPG; PRO9904; 2310069M11Rik; epigen; EPGN_HUMAN; EPGN; Epithelial mitogen (EPG); EPGN_MOUSE; epithelial mitogen; epithelial mitogen homolog (mouse)
Dilution WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name EPGN
Function Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
Cellular Location [Isoform 1]: Membrane; Single-pass type I membrane protein [Isoform 3]: Secreted. [Isoform 5]: Secreted.
Research Areas
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