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ITIH1 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | P19827 |
| Other Accession | P19827 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 101389 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human ITIH1 |
| Epitope Specificity | 195-290/911 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the ITIH family.Contains 1 VIT domain.Contains 1 VWFA domain. |
| SUBUNIT | I-alpha-I plasma protease inhibitors are assembled from one or two heavy chains (H1, H2 or H3) and one light chain, bikunin. Inter-alpha-inhibitor (I-alpha-I) is composed of H1, H2 and bikunin, inter-alpha-like inhibitor (I-alpha-LI) of H2 and bikunin, and pre-alpha-inhibitor (P-alpha-I) of H3 and bikunin. |
| Post-translational modifications | Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage. The S-linked glycan is composed of two 6-carbon sugars, possibly Glc or Gal. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells. |
| Gene ID | 3697 |
|---|---|
| Other Names | H1P; IATIH; IGHEP1; ITI-HC1; ITIH; SHAP; ITIH1_HUMAN; ITIH1; ITI heavy chain H1; Inter-alpha-inhibitor heavy chain 1; Inter-alpha-trypsin inhibitor complex component III; Serum-derived hyaluronan-associated protein (SHAP); inter-alpha-trypsin inhibitor heavy chain 1; inter-alpha (globulin) inhibitor, H1 polypeptide |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ITIH1 |
|---|---|
| Synonyms | IGHEP1 |
| Function | May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. |
| Cellular Location | Secreted. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP97429
