癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
NDUFA2 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | O43678 |
| Other Accession | O43678 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 10922 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human NDUFA2 |
| Epitope Specificity | 2-80/99 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBUNIT | Complex I is composed of 45 different subunits. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
| Gene ID | 4695 |
|---|---|
| Other Names | B8; CD14; CIB8; MC1DN13; C1-B8; CI-B8; NDUA2_MACFA; NDUFA2; Complex I-B8 (CI-B8); NADH-ubiquinone oxidoreductase B8 subunit; NDUA2_GORGO; NDUA2_HUMAN; NDUA2_MOUSE; NDUA2_PONAB; NADH:ubiquinone oxidoreductase subunit A2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2 (8kD, B8); NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa; complex I B8 subunit |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | NDUFA2 |
|---|---|
| Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
| Cellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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