癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
GAPDHS Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | O14556 |
| Other Accession | O14556 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 44501 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human GAPDHS |
| Epitope Specificity | 251-350/408 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the glyceraldehyde-3-phosphatedehydrogenase family. |
| SUBUNIT | Homotetramer. Interacts with ARRB2; the interaction isdetected in the nucleus upon OR1D2 stimulation. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene encodes a protein belonging to theglyceraldehyde-3-phosphate dehydrogenase family of enzymes thatplay an important role in carbohydrate metabolism. Like its somaticcell counterpart, this sperm-specific enzyme functions in anicotinamide adenine dinucleotide-dependent manner to removehydrogen and add phosphate to glyceraldehyde 3-phosphate to form1,3-diphosphoglycerate. During spermiogenesis, this enzyme may playan important role in regulating the switch between differentenergy-producing pathways, and it is required for sperm motilityand male fertility. [provided by RefSeq, Jul 2008]. |
| Gene ID | 26330 |
|---|---|
| Other Names | G3PT_BOVIN; GAPDHS; Spermatogenic glyceraldehyde-3-phosphate dehydrogenase; 1.2.1.12; G3PT_HUMAN; Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2 (GAPDH-2); GAPD2; GAPDH2; GAPDS; G3PT_MOUSE; Gapd-s; G3PT_RAT; glyceraldehyde-3-phosphate dehydrogenase, spermatogenic |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | GAPDHS (HGNC:24864) |
|---|---|
| Synonyms | GAPD2, GAPDH2, GAPDS |
| Function | Catalyzes the conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate in glycolysis and the reverse reaction in gluconeogenesis (By similarity). May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Testis specific. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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