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RERE Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q9P2R6 |
| Other Accession | Q9P2R6 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 172424 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human RERE |
| Epitope Specificity | 521-620/1566 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Contains 1 BAH domain. Contains 1 ELM2 domain. Contains 1 GATA-type zinc finger. Contains 1 SANT domain. |
| SUBUNIT | Interacts with HDAC1 (By similarity). Interacts with ATN1. Interaction with ATN1 is improved when the poly-Gln region of ATN1 is extended. Interacts with FAT1. |
| DISEASE | Note=A chromosomal aberration involving RERE is found in the neuroblastoma cell line NGP. Translocation t(1;15)(p36.2;q24). |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | FunctionPlays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death. |
| Gene ID | 473 |
|---|---|
| Other Names | ARG; ARP; ATN1L; DNB1; NEDBEH; RERE_HUMAN; RERE; Atrophin-1-like protein; Atrophin-1-related protein; KIAA0458; arginine-glutamic acid dipeptide repeats; arginine-glutamic acid dipeptide (RE) repeats; atrophin 2 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | RERE |
|---|---|
| Synonyms | ARG, ARP, ATN1L, KIAA0458 |
| Function | Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00512, ECO:0000255|PROSITE-ProRule:PRU00624, ECO:0000269|PubMed:10814707, ECO:0000269|PubMed:11331249}. Note=Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs |
| Tissue Location | Widely expressed. Expressed in tumor cell lines. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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