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ZNF277 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q9NRM2 |
| Other Accession | Q9NRM2 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 52788 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human ZNF277 |
| Epitope Specificity | 201-300/450 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the ZNF277 family. Contains 2 C2H2-type zinc fingers. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Several mammalian kinases have been identified with sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase STE20. STE20 is involved in relaying signals from G-protein coupled receptors to cytosolic MAP kinase cascades, and it lies upstream of a MAP kinase kinase kinase. Mammalian STE20-like kinases include KHS, GLK, NIK, YSK1, HPK1, Krs-1, Krs-2 and GC kinase. KHS (for kinase homologous to SPS1/STE20) is a protein that is most closely related to GC kinase. The KHS kinase has been shown to activate a variety of substrates, including JNK, suggesting a role in stress response. |
| Gene ID | 11179 |
|---|---|
| Other Names | NRIF4; ZNF277P; ZN277_HUMAN; ZNF277; Nuclear receptor-interacting factor 4; zinc finger protein 277; zinc finger protein (C2H2 type) 277; zinc finger protein 277 pseudogene |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ZNF277 |
|---|---|
| Synonyms | NRIF4, ZNF277P |
| Function | Probable transcription factor. Involved in modulation of cellular senescence; represses transcription of the tumor suppressor gene INK4A/ARF, perhaps acting via the Polycomb group (PcG) complex PRC1. |
| Cellular Location | Nucleus. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP97577
