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Salusin alpha Rabbit pAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P, IHC-F, IF, E
Primary Accession Q5JU69
Other Accession Q5JU69
Predicted Rat, Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 35714 Da
Physical State Liquid
Immunogen KLH conjugated synthetic peptide derived from human Salusin alpha
Epitope Specificity 51-150/321
Isotype IgG
Purity affinity purified by Protein A
Buffer 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SIMILARITY Belongs to the clpA/clpB family. Torsin subfamily.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions bs-9875P is one synthetic peptide derived from human Salusin alpha. Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis; it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.
Additional Information
Gene ID 27433
Other Names TORP1; TOR2A_HUMAN; TOR2A; Torsin family 2 member A; Torsin-related protein 1; torsin family 2, member A
Dilution IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name TOR2A
Synonyms TORP1
Cellular Location Endoplasmic reticulum lumen.
Tissue Location Isoform 1 is expressed ubiquitously, except in cardiac and endothelial tissues.
Research Areas
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