癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
CTDSP2 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | O14595 |
| Other Accession | O14595 |
| Reactivity | Rat, Human |
| Predicted | Pig, Mouse, Rabbit, Horse, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 30664 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human CTDSP2 |
| Epitope Specificity | 25-150/271 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Contains 1 FCP1 homology domain. |
| SUBUNIT | Monomer (By similarity). Interacts with REST. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Gene ID | 10106 |
|---|---|
| Other Names | OS4; PSR2; SCP2; D10Ertd73e; OS-4; CTDS2_HUMAN; CTDSP2; Nuclear LIM interactor-interacting factor 2 (NLI-interacting factor 2); Protein OS-4; Small C-terminal domain phosphatase 2; Small CTD phosphatase 2 (SCP2); 3.1.3.16; NIF2; CTDS2_MOUSE; CTD small phosphatase 2; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2; conserved gene amplified in osteosarcoma; nuclear LIM interactor-interacting factor 2; NLI-interacting factor 2; small CTD phosphatase 2 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CTDSP2 |
|---|---|
| Synonyms | NIF2, OS4, SCP2 |
| Function | Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. |
| Cellular Location | Nucleus. |
| Tissue Location | Expression is restricted to non-neuronal tissues. Highest expression in pancreas and lowest in liver |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,980.00
Cat# AP97621
