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PCDHGB4 Rabbit pAb

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Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	IHC-P, IHC-F, IF, E
Predicted	Rat, Pig, Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Calculated MW	97 KDa
Physical State	Liquid
Immunogen	KLH conjugated synthetic peptide derived from human PCDHGB4
Epitope Specificity	101-200/923
Isotype	IgG
Purity	affinity purified by Protein A
Buffer	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SIMILARITY	Contains 6 cadherin domains.
SUBUNIT	Contains 6 cadherin domains.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions	The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-20, also known as protocadherin gamma B4, is a member of the protocadherin gamma gene cluster. Expressed primariy in fibroblasts, cadherin-20 plays a critical role in neuronal cell-cell connections in the brain. Through its ability to mediate cell-cell adhesion, caderin-20 is thought to help the body respond to injury by regulating post-traumatic wound healing.

Additional Information
Gene ID	8641
Other Names	CDH20; FIB2; PCDH-GAMMA-B4; protocadherin gamma subfamily B, 4; fibroblast cadherin FIB2; cadherin 20
Dilution	IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Name	PCDHGB4 Rabbit pAb
Function	Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.