LINGO2 Rabbit pAb

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Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P, IHC-F, IF, E
Primary Accession	Q7L985
Other Accession	Q7L985
Reactivity	Human
Predicted	Rat, Pig, Mouse, Zebrafish, Chicken, Dog, Horse
Host	Rabbit
Clonality	Polyclonal
Calculated MW	68066 Da
Physical State	Liquid
Immunogen	KLH conjugated synthetic peptide derived from human LINGO2
Epitope Specificity	331-430/606
Isotype	IgG
Purity	affinity purified by Protein A
Buffer	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SIMILARITY	Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 12 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions	Lingo-2 (leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2), also known as LERN3 (leucine-rich repeat neuronal protein 3) or LRRN6C, is a 606 amino acid single-pass type I membrane protein. Lingo-2 contains 1 immunoglobulin-like C2-type domain and 13 leucine-rich repeats. Lingo-2 is a member of the LRR gene family and has been linked to essential tremor and Parkinson’s disease. Lingo-2 has a high degree of homology (61%) with Lingo-1, a regulator of neuronal death, and the expression of Lingo-2 seems to be restricted to neuronal tissue.

Additional Information
Gene ID	158038
Other Names	LERN3; LRRN6C; B230217C06Rik; LIGO2_HUMAN; LINGO2; Leucine-rich repeat neuronal protein 3; Leucine-rich repeat neuronal protein 6C; LIGO2_MOUSE; leucine rich repeat and Ig domain containing 2; leucine rich repeat neuronal 6C
Dilution	WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

For Research Use Only. Not For Use In Diagnostic Procedures.