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GPR70 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q7RTX1 |
| Other Accession | Q7RTX1 |
| Predicted | Rat, Human, Mouse, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 93074 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human GPR70/T1R1 |
| Epitope Specificity | 441-550/841 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily. |
| SUBUNIT | Forms heterodimers with TAS1R3. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] |
| Gene ID | 80835 |
|---|---|
| Other Names | GM148; GPR70; T1R1; TR1; TS1R1_HUMAN; TAS1R1; G-protein coupled receptor 70; TS1R1_MOUSE; TS1R1_RAT; taste 1 receptor member 1; G protein-coupled receptor 70; taste receptor, type 1, member 1 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | TAS1R1 |
|---|---|
| Synonyms | GPR70, T1R1, TR1 |
| Function | Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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