癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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LHX2 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | P50458 |
| Other Accession | P50458 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 44373 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human LHX2 |
| Epitope Specificity | 251-330/406 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Contains 1 homeobox DNA-binding domain.Contains 2 LIM zinc-binding omains. |
| SUBUNIT | Contains 1 homeobox DNA-binding domain. Contains 2 LIM zinc-binding domains. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | During development, genetically distinct subtypes of motor neurons express unique combinations of LIM-type homeodomain factors, which regulate cell migration and guide motor axons to establish the fidelity of a binary choice in axonal trajectory. The LIM gene family encodes a set of gene products, which carry the LIM domain, a unique cysteine-rich zinc-binding domain. At least 40 members of this family have been identified in vertebrates and invertebrates, and are distributed into 4 groups according to the number of LIM domains and to the presence of homeodomains and kinase domains. The overlapping expression of LHX1, LHX3, LHX4, Isl-1 and Isl-2 in developing motor neurons along the spinal column may influence the establishment of specific motor neuron subtypes. The human LHX2 gene maps to chromosome 9q33.3 and encodes a 389 amino acid protein. LHX2 is involved in early patterning of the telencephalon, where the neuroepithelium is first divided into cortical tissue and cortical hem. |
| Gene ID | 9355 |
|---|---|
| Other Names | LH2A; Lh-2; Lim2; ap; apterous; LHX2_MOUSE; Lhx2; Homeobox protein LH-2; LIM homeobox protein 2; LHX2_RAT; Lh2; LHX2_HUMAN; hLhx2; LIM homeobox 2; LIM/homeobox protein Lhx2 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,Flow-Cyt=1 µg/Test |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | LHX2 |
|---|---|
| Synonyms | LH2 |
| Function | Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types (By similarity). |
| Cellular Location | Nucleus. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP97678
