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ZP3 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | P21754 |
| Other Accession | P21754 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 47018 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human ZP3 |
| Epitope Specificity | 101-200/424 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| SIMILARITY | Belongs to the ZP domain family. ZPC subfamily. Contains 1 ZP domain. |
| Post-translational modifications | Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. N-glycosylated. O-glycosylated; removal of O-linked glycans may play an important role in the post-fertilization block to polyspermy. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. |
| Gene ID | 7784 |
|---|---|
| Other Names | Zp-3; Zp-3B; OOMD3; OZEMA3; ZP3A; ZP3B; ZPC; ZP3_BOVIN; ZP3; Sperm receptor; Zona pellucida glycoprotein 3 (Zp-3); Zona pellucida glycoprotein 3B (Zp-3B); Zona pellucida protein C; ZP3_HUMAN; ZP3A/ZP3B; zona pellucida glycoprotein 3; zona pellucida glycoprotein 3A (sperm receptor) |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ZP3 |
|---|---|
| Synonyms | ZP3A, ZP3B, ZPC |
| Function | Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. |
| Cellular Location | [Processed zona pellucida sperm-binding protein 3]: Zona pellucida |
| Tissue Location | Expressed in oocytes (at protein level). |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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