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AATK Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q6ZMQ8 |
| Other Accession | Q6ZMQ8 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 144569 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human AATK |
| Epitope Specificity | 1201-1374/1374 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the protein kinase superfamily. Tyr protein kinase family. Contains 1 protein kinase domain. |
| SUBUNIT | Interacts with CDK5. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011] |
| Gene ID | 9625 |
|---|---|
| Other Names | AATYK; AATYK1; LMR1; LMTK1; PPP1R77; p35BP; LMTK1_HUMAN; AATK; Apoptosis-associated tyrosine kinase (AATYK); Brain apoptosis-associated tyrosine kinase; CDK5-binding protein; Lemur tyrosine kinase 1; p35-binding protein (p35BP); 2.7.11.1; KIAA0641; apoptosis associated tyrosine kinase; protein phosphatase 1, regulatory subunit 77 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | AATK |
|---|---|
| Synonyms | AATYK, KIAA0641, LMR1, LMTK1 |
| Function | May be involved in neuronal differentiation. |
| Cellular Location | Membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Note=Predominantly perinuclear |
| Tissue Location | Expressed in brain.. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP97870
