癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KIAA1688 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q9C0H5 |
| Other Accession | Q9C0H5 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 121286 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human KIAA1688 |
| Epitope Specificity | 801-900/1083 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Contains 1 MyTH4 domain.Contains 1 Rho-GAP domain.Contains 2 WW domains. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in down regulation of their active form. KIAA1688, also known as ARHGAP39 (Rho GTPase activating protein 39), CrGAP or Vilse, is a 1,083 amino acid nuclear protein that contains one MyTH4 domain, one Rho-GAP domain and two WW domains. KIAA1688 is encoded by a gene located on human chromosome 8, which consists of nearly 146 million bases and encodes approximately 800 genes. Chromosome 8 is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8. |
| Gene ID | 80728 |
|---|---|
| Other Names | CrGAP; Vilse; RHG39_HUMAN; ARHGAP39; KIAA1688; RHG39_MOUSE; D15Wsu169e; Rho GTPase activating protein 39; RhoGAP93B homolog (Drosophila); crossGAP homolog (Drosophila) |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ARHGAP39 |
|---|---|
| Synonyms | KIAA1688 |
| Cellular Location | Nucleus. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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