DPEP2 Rabbit pAb
- 产品详情
- 实验流程
Application
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q9H4A9 |
| Other Accession | Q9H4A9 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 53365 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human DPEP2 |
| Epitope Specificity | 101-200/486 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the peptidase M19 family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | DPEP2 belongs to the membrane-bound dipeptidase (EC 3.4.13.19) family. These enzymes hydrolyze a variety of dipeptides, including leukotriene D4, the beta-lactam ring of some antibiotics, and cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation (Habib et al., 2003 [PubMed 12738806]).[supplied by OMIM, Mar 2008] |
| Gene ID | 64174 |
|---|---|
| Other Names | MBD2; DPEP2_HUMAN; DPEP2; 3.4.13.19; dipeptidase 2 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | DPEP2 |
|---|---|
| Function | Dipeptidase that hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4) (PubMed:32325220). Hydrolyzes cystinyl-bis- glycine (PubMed:32325220). |
| Cellular Location | Membrane {ECO:0000250|UniProtKB:Q8C255}; Lipid- anchor, GPI-anchor {ECO:0000250|UniProtKB:Q8C255} |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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