癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KIAA2022 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q5QGS0 |
| Other Accession | Q5QGS0 |
| Reactivity | Rat, Mouse |
| Predicted | Pig, Human, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 167551 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human KIAA2022 |
| Epitope Specificity | 1151-1160/1516 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBUNIT | Cytoplasm; Nucleus |
| DISEASE | Intellectual developmental disorder, X-linked 98 (XLID98) |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | An inversion on the X chromosome which disrupts this gene and a G-protein coupled purinergic receptor gene located in the pseudoautosomal region of the X chromosome has been linked to X linked cognitive disability.[provided by RefSeq, Mar 2009] |
| Gene ID | 340533 |
|---|---|
| Other Names | NEXMI_HUMAN; NEXMIF; XLMR protein related to neurite extension (XPN); KIAA2022; KIDLIA; MRX98; XLID98; XPN; neurite extension and migration factor; XLMR-related protein, neurite extension |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | NEXMIF (HGNC:29433) |
|---|---|
| Function | Involved in neurite outgrowth by regulating cell-cell adhesion via the N-cadherin signaling pathway. May act by regulating expression of protein-coding genes, such as N-cadherins and integrin beta-1 (ITGB1). |
| Cellular Location | Nucleus. Cytoplasm {ECO:0000250|UniProtKB:Q5DTT1} |
| Tissue Location | Highly expressed in fetal and adult brain, predominantly in the cerebral cortex and the cerebellum. Also expressed in other tissues but to a lesser extent. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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