癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
FOXG1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- 文献引用 : 1
- 实验流程
- 背景知识
Application 
| WB, IF, FC, E |
|---|---|
| Primary Accession | P55316 |
| Other Accession | P32031, Q9YHC5, Q00939, Q60987, Q90964 |
| Reactivity | Human, Mouse, Rat |
| Predicted | Rat, Chicken, Drosophila, Xenopus |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 52352 Da |
| Antigen Region | 225-252 aa |
| Gene ID | 2290 |
|---|---|
| Other Names | Forkhead box protein G1, Brain factor 1, BF-1, BF1, Brain factor 2, BF-2, BF2, hBF-2, Forkhead box protein G1A, Forkhead box protein G1B, Forkhead box protein G1C, Forkhead-related protein FKHL1, HFK1, Forkhead-related protein FKHL2, HFK2, Forkhead-related protein FKHL3, HFK3, FOXG1 |
| Target/Specificity | This FOXG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-252 amino acids from the Central region of human FOXG1. |
| Dilution | WB~~1:1000 IF~~1:10~50 FC~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FOXG1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FOXG1 |
|---|---|
| Function | Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089, ECO:0000269|PubMed:21280142} |
| Tissue Location | Expression is restricted to the neurons of the developing telencephalon. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of the brain and telencephalon.
REFERENCES
Mencarelli, M.A., et al. J. Med. Genet. 47(1):49-53(2010)
Philippe, C., et al. J. Med. Genet. 47(1):59-65(2010)
Ariani, F., et al. Am. J. Hum. Genet. 83(1):89-93(2008)
Adesina, A.M., et al. J. Neurooncol. 85(2):111-122(2007)
Bredenkamp, N., et al. Dev. Genes Evol. 217(3):227-233(2007)
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