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SFRS17A Rabbit pAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P, IHC-F, IF
Primary Accession Q02040
Other Accession Q02040
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 80735 Da
Physical State Liquid
Immunogen KLH conjugated synthetic peptide derived from human SFRS17A
Epitope Specificity 501-600/695
Isotype IgG
Purity affinity purified by Protein A
Buffer Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
SUBUNIT Contains 1 RRM (RNA recognition motif) domain.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Sep 2010]
Additional Information
Gene ID 8227
Other Names 721P; AKAP-17A; CCDC133; CXYorf3; DXYS155E; PRKA17A; SFRS17A; XE7; XE7Y; AK17A_HUMAN; AKAP17A; B-lymphocyte antigen; Protein XE7; Protein kinase A-anchoring protein 17A (PRKA17A); Splicing factor, arginine/serine-rich 17A; A-kinase anchoring protein 17A; chromosome X and Y open reading frame 3; A kinase (PRKA) anchor protein 17A
Dilution IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name AKAP17A
Synonyms CXYorf3, DXYS155E, SFRS17A, XE7
Function Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner.
Cellular Location Nucleus speckle
Tissue Location Widely expressed. Found in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Expressed in activated B- cells and placenta. Expressed in all cell lines tested including Jurkat-TAg, U-937 and HEK293 cells.
Research Areas
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