癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
HRSP12 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | P52758 |
| Other Accession | P52758 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 14494 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human HRSP12 |
| Epitope Specificity | 51-137/137 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the RutC family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA. |
| Gene ID | 10247 |
|---|---|
| Other Names | HRSP12; P14.5; PSP; UK114; hp14.5; RIDA_BOVIN; RIDA; Translation inhibitor L-PSP ribonuclease; 3.5.99.10; RIDA_CAPHI; 14.3 kDa perchloric acid soluble protein; UK114 antigen; RIDA_HUMAN; 14.5 kDa translational inhibitor protein (hp14.5 | p14.5); Heat-responsive protein 12; Reactive intermediate imine deaminase A homolog; UK114 antigen homolog; reactive intermediate imine deaminase A; translational inhibitor p14.5; reactive intermediate/imine deaminase A homolog; 2-iminobutanoate/2-iminopropanoate deaminase |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | RIDA (HGNC:16897) |
|---|---|
| Function | Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'- phosphate-dependent dehydratases including L-threonine dehydratase. |
| Cellular Location | Cytoplasm. Nucleus. Peroxisome {ECO:0000250|UniProtKB:P52759}. Mitochondrion {ECO:0000250|UniProtKB:P52759}. Note=Mostly cytoplasmic but, in less differentiated cells occasionally nuclear |
| Tissue Location | Expressed predominantly in liver and kidney. Lower levels in lung and brain. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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