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Ketohexokinase Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | P50053 |
| Other Accession | P50053 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 32523 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human Ketohexokinase |
| Epitope Specificity | 151-250/298 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the carbohydrate kinase PfkB family. |
| SUBUNIT | Homodimer. |
| DISEASE | Defects in KHK are the cause of fructosuria (FRUCT) [MIM:229800]. Benign defect of intermediary metabolism. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| Gene ID | 3795 |
|---|---|
| Other Names | FRUCTU; KHK_HUMAN; KHK; Hepatic fructokinase; 2.7.1.3; Q6IBK2_HUMAN; KHK_MOUSE; ketohexokinase; ketohexokinase (fructokinase); fructokinase |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | KHK (HGNC:6315) |
|---|---|
| Function | Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate. |
| Tissue Location | Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP98042
