癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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TMED4 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q7Z7H5 |
| Other Accession | Q7Z7H5 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 25943 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human TMED4 |
| Epitope Specificity | 41-140/227 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the EMP24/GP25L family. Contains 1 GOLD domain. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | TMED4 is a putative NF-kB activating protein belonging to the EMP24/GP25L family, and contains 1 GOLD domain. It is also known as Transmembrane emp24 protein transport domain containing 4. |
| Gene ID | 222068 |
|---|---|
| Other Names | ERS25; GMP25iso; HNLF; p24a3; p24alpha3; 1110014L17Rik; RGD1306319; TMED4_HUMAN; TMED4; Endoplasmic reticulum stress-response protein 25 (ERS25); Putative NF-kappa-B-activating protein 156; p24 family protein alpha-3 (p24alpha3); TMED4_MOUSE; p26; transmembrane p24 trafficking protein 4; transmembrane emp24 protein transport domain containing 4 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | TMED4 |
|---|---|
| Synonyms | ERS25 |
| Function | Involved in vesicular protein trafficking, mainly in the early secretory pathway. targeting. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis (By similarity). |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP98104
