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ADAM23 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | O75077 |
| Other Accession | O75077 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 91926 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human ADAM23 |
| Epitope Specificity | 551-650/832 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Contains 1 disintegrin domain.Contains 1 EGF-like domain.Contains 1 peptidase M12B domain. |
| SUBUNIT | Can bind to LGI1 and LGI4 (By similarity). Ligand for integrin alpha-V/beta-3. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | ADAM23 is a non-catalytic metalloprotease-like protein. It is highly expressed in the brain, primarily in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole, and weakly expressed in the heart. 3 isoforms are produced by alternative splicing, alpha, beta and gamma. ADAM23 may play a role in cell-cell and cell-matrix interactions. |
| Gene ID | 8745 |
|---|---|
| Other Names | MDC-3; MDC3; ADA23_HUMAN; ADAM23; ADAM 23; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3 (MDC-3); ADA23_MOUSE; ADAM metallopeptidase domain 23; a disintegrin and metalloproteinase domain 23 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,Flow-Cyt=0.2ug/Test |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ADAM23 |
|---|---|
| Synonyms | MDC3 |
| Function | May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP98186
