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Syntrophin-2 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q13884 |
| Other Accession | Q13884 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 58061 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human Syntrophin-2 |
| Epitope Specificity | 51-150/538 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the syntrophin family.Contains 1 PDZ (DHR) domain. Contains 2 PH domains. Contains 1 SU (syntrophin unique) domain. |
| SUBUNIT | Monomer and homodimer (Probable). Interacts with the other members of the syntrophin family SNTA1 and SNTB2; with the sodium channel proteins SCN4A and SCN5A. Interacts with the viral HTLV-1 TAX protein and with dystrophin protein DMD and related proteins DTNA and UTRN. |
| Post-translational modifications | Phosphorylated by CaM-kinase II. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008]. |
| Gene ID | 6641 |
|---|---|
| Other Names | 59-DAP; A1B; BSYN2; DAPA1B; SNT2; SNT2B1; TIP-43; SNTB1_HUMAN; SNTB1; 59 kDa dystrophin-associated protein A1 basic component 1 (DAPA1B); Syntrophin-2; Tax interaction protein 43 (TIP-43); syntrophin beta 1; syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1); tax interaction protein 43 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SNTB1 |
|---|---|
| Synonyms | SNT2B1 |
| Function | Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. |
| Cellular Location | Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell junction. Cytoplasm, cytoskeleton. Note=In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane and at neuromuscular junctions |
| Tissue Location | Ubiquitous.. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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