癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Myosin heavy chain 2 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q9UKX2 |
| Other Accession | Q9UKX2 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 223044 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human Myosin-2 |
| Epitope Specificity | 751-850/1941 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Contains 1 IQ domain.Contains 1 myosin head-like domain. |
| SUBUNIT | Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Interacts with GCSAM. |
| DISEASE | Inclusion body myopathy 3 (IBM3) [MIM:605637]: Hereditary inclusion body myopathies constitute a group of neuromuscular disorders characterized by slowly progressive distal and proximal weakness and a typical muscle pathology including rimmed vacuoles and filamentous inclusions. IBM3 is a variant of hereditary inclusion body myopathies and is characterized by autosomal dominant myopathy with joint contracture, ophthalmoplegia and rimmed vacuoles. Morphological analysis of muscle biopsies from patients indicate that the type 2A fibers frequently were abnormal, whereas other fiber types appeared normal. Note=The disease is caused by mutations affecting the gene represented in this entry. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Gene ID | 4620 |
|---|---|
| Other Names | CMYO6; CMYP6; IBM3; MYH2A; MYHSA2; MYHas8; MYPOP; MyHC-2A; MyHC-IIa; MYH2_HUMAN; MYH2; Myosin heavy chain 2; Myosin heavy chain 2a (MyHC-2a); Myosin heavy chain IIa (MyHC-IIa); Myosin heavy chain, skeletal muscle, adult 2; myosin, heavy polypeptide 2, skeletal muscle, adult; inclusion body myopathy 3, autosomal dominant |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | MYH2 (HGNC:7572) |
|---|---|
| Synonyms | MYHSA2 |
| Function | Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. |
| Cellular Location | Cytoplasm, myofibril {ECO:0000250|UniProtKB:G3UW82}. Note=Thick filaments of the myofibrils |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP98280
