YY1AP1 Rabbit pAb

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P, IHC-F, IF, E
Primary Accession	Q9H869
Other Accession	Q9H869
Host	Rabbit
Clonality	Polyclonal
Calculated MW	87944 Da
Physical State	Liquid
Immunogen	KLH conjugated synthetic peptide derived from human YY1AP1/HCCA2
Epitope Specificity	301-400/796
Isotype	IgG
Purity	affinity purified by Protein A
Buffer	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SUBUNIT	Interacts with YY1. Interacts with MAD2L2.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions	Enhances transcription activation by YY1. Tissue specificity:Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.

Additional Information
Gene ID	55249
Other Names	GRNG; HCCA1; HCCA2; YY1AP; YYAP1_HUMAN; YY1AP1; Hepatocellular carcinoma susceptibility protein; Hepatocellular carcinoma-associated protein 2; YY1 associated protein 1
Dilution	WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name	YY1AP1 (HGNC:30935)
Function	Associates with the INO80 chromatin remodeling complex, which is responsible for transcriptional regulation, DNA repair, and replication (PubMed:27939641). Enhances transcription activation by YY1 (PubMed:14744866). Plays a role in cell cycle regulation (PubMed:17541814, PubMed:27939641).
Cellular Location	Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus
Tissue Location	Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.