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DHX32 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q7L7V1 |
| Other Accession | Q7L7V1 |
| Reactivity | Rat |
| Predicted | Pig, Human, Mouse, Rabbit, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 84419 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human DHX32 |
| Epitope Specificity | 561-660/743 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the DEAD box helicase family. DEAH subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX32 is a 743 amino acid nuclear protein that localizes to the mitochondria and is a member of the DEAD box helicase family. Expressed in various tissues, DDX32 is up-regulated by ionomycin in T lymphocytes and down-regulated in acute lymphoblastic leukemia. Considered a novel RNA helicase, DDX32 may play an important role in the development of colorectal cancer and may be involved in regulating T-cell response to certain apoptotic stimuli. |
| Gene ID | 55760 |
|---|---|
| Other Names | DDX32; DHLP1; 4732469F02Rik; muDDX32; DHX32_HUMAN; DHX32; DEAD/H box 32; DEAD/H helicase-like protein 1 (DHLP1); DEAH box protein 32; HuDDX32; 3.6.4.13; DHX32_MOUSE; DEAH-box helicase 32 (putative); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32; DEAH (Asp-Glu-Ala-His) box polypeptide 32; DEAD/H helicase-like protein 1; Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | DHX32 |
|---|---|
| Synonyms | DDX32 |
| Cellular Location | Nucleus. Mitochondrion |
| Tissue Location | Expressed in lymphoid tissues (at protein level). Expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung, lymphoid tissues and blood leukocytes. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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