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TM7SF2 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | O76062 |
| Other Accession | O76062 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 46406 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human TM7SF2/DHCR14A |
| Epitope Specificity | 51-150/418 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the ERG4/ERG24 family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Involved in the conversion of lanosterol to cholesterol.Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes. |
| Gene ID | 7108 |
|---|---|
| Other Names | ANG1; C14SR; DHCR14A; NET47; 3110041O18Rik; Dhcr14; ERG24_HUMAN; TM7SF2; Delta-14-SR; 3-beta-hydroxysterol Delta (14)-reductase; Another new gene 1 protein; C-14 sterol reductase (C14SR); Putative sterol reductase SR-1; Sterol C14-reductase; Transmembrane 7 superfamily member 2; 1.3.1.70; ERG24_MOUSE; delta(14)-sterol reductase |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | TM7SF2 |
|---|---|
| Synonyms | ANG1 |
| Function | Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis. |
| Cellular Location | Microsome membrane {ECO:0000250|UniProtKB:Q71KT5}; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, testis and adrenal gland, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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