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为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SAHH Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | P23526 |
| Other Accession | P23526 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 47716 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human SAHH |
| Epitope Specificity | 25-125/432 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the adenosylhomocysteinase family. |
| SUBUNIT | Homotetramer. |
| DISEASE | Defects in AHCY are the cause of hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) [MIM:613752]. A metabolic disorder characterized by hypermethioninemia associated with failure to thrive, mental and motor retardation, facial dysmorphism with abnormal hair and teeth, and myocardiopathy. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. |
| Gene ID | 191 |
|---|---|
| Other Names | SAHH; adoHcyase; CuBP; SAHH_HUMAN; AHCY; S-adenosyl-L-homocysteine hydrolase; 3.13.2.1; SAHH_MOUSE; Liver copper-binding protein; SAHH_RAT; adenosylhomocysteinase; S-adenosylhomocysteine hydrolase |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,Flow-Cyt=1ug/Test |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | AHCY |
|---|---|
| Synonyms | SAHH |
| Function | Catalyzes the hydrolysis of S-adenosyl-L-homocysteine to form adenosine and homocysteine (PubMed:10933798). Binds copper ions (By similarity). |
| Cellular Location | Cytoplasm. Melanosome. Nucleus. Endoplasmic reticulum. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP98712
