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MURF3 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q9BYV2 |
| Other Accession | Q9BYV2 |
| Predicted | Rat, Pig, Human, Mouse, Rabbit, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 40301 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human MURF3 |
| Epitope Specificity | 131-240/358 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Contains 1 B box-type zinc finger. Contains 1 COS domain. Contains 1 RING-type zinc finger. |
| SUBUNIT | Homooligomer and heterooligomer. Interacts with tubulin (By similarity). Interacts with TRIM63 and probably with TRIM55. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | MuRF3, also designated tripartite motif-containing 54 (TRIM54) or ring finger protein 30 (RNF30), interacts with tubulin and stabilizes microtubules duing myotube formation. It is a cytoplasmic protein the localizes to the Z-lines in skeletal muscles, while MuRF2 localizes to the sarcomeric M-band in cardiomyocytes. MuRF3 shares 77% and 65% sequence identity with MuRF1 and MuRF2, respectively. MuRF1-3 share a conserved N-terminal RING domain and zinc-binding B-box motif, and two coiled-coil dimerization motif boxes, in their central regions. |
| Gene ID | 57159 |
|---|---|
| Other Names | MURF; MURF-3; RNF30; muRF3; TRI54_HUMAN; TRIM54; Muscle-specific RING finger protein (MuRF); Muscle-specific RING finger protein 3 (MuRF-3 | MuRF3); RING finger protein 30; tripartite motif containing 54; tripartite motif-containing 54 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | TRIM54 |
|---|---|
| Synonyms | MURF, MURF3, RNF30 |
| Function | May bind and stabilize microtubules during myotubes formation. |
| Cellular Location | Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Note=Associates with microtubules. Localizes to the Z-lines in skeletal muscles (By similarity). |
| Tissue Location | Specifically expressed in heart and skeletal muscle. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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