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LMO2 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | P25791 |
| Other Accession | P25791 |
| Predicted | Rat, Human, Mouse, Chicken, Dog, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 18358 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human LMO2 |
| Epitope Specificity | 71-158/158 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Contains 2 LIM zinc-binding domains. |
| SUBUNIT | Interacts via its LIM domains with ELF2 and LBD1. Also interacts with basic helix-loop-helix protein TAL1/SCL and can assemble in a complex with LMO2 and TAL1/SCL (By similarity). Interacts with BEX2 and KDM5A. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008] |
| Gene ID | 4005 |
|---|---|
| Other Names | LMO-2; RBTN2; RBTNL1; RHOM2; TTG2; Rbtn-2; Rhom-2; RBTN2_HUMAN; LMO2; Cysteine-rich protein TTG-2; LIM domain only protein 2 (LMO-2); T-cell translocation protein 2; RBTN2_MOUSE; LIM domain only 2; rhombotin-like 1; T-cell translocation gene 2 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | LMO2 |
|---|---|
| Synonyms | RBTN2, RBTNL1, RHOM2, TTG2 |
| Function | Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state. |
| Cellular Location | Nucleus. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP98885
