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JAKMIP1/GABABRBP Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q96N16 |
| Other Accession | Q96N16 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 73209 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human GABABRBP/JAKMIP1 |
| Epitope Specificity | 20-120/626 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the JAKMIP family. |
| SUBUNIT | Homodimer. Forms a complex with GABBR1 and KIF5B/kinesin-1. Interacts with JAK1 and TYK2. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. |
| Gene ID | 152789 |
|---|---|
| Other Names | Gababrbp; JAMIP1; MARLIN1; 5830437M04Rik; C330021K24Rik; Marlin-1; JKIP1_HUMAN; JAKMIP1; GABA-B receptor-binding protein; Multiple alpha-helices and RNA-linker protein 1 (Marlin-1); JKIP1_MOUSE; JKIP1_RAT; Multiple alpha helices and RNA-linker protein 1 (Marlin-1); janus kinase and microtubule interacting protein 1 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | JAKMIP1 |
|---|---|
| Synonyms | GABABRBP, JAMIP1, MARLIN1 |
| Function | Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. |
| Cellular Location | Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Colocalizes with the microtubule network Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells |
| Tissue Location | Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP98963
