癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
NXPH4 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | O95158 |
| Other Accession | O95158 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 33065 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human NXPH4 |
| Epitope Specificity | 241-308/308 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| SIMILARITY | Belongs to the neurexophilin family. |
| Post-translational modifications | May be proteolytically processed at the boundary between the N-terminal non-conserved and the central conserved domain in neuron-like cells. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | NXPH4 is a neurexophilin. Mammalian brains contain four different neurexophilin proteins. Neurexophilins form a family of related glycoproteins that are proteolytically processed after synthesis and bind to alpha neurexins. The structure and characteristics of neurexophilins indicate that they function as neuropeptides that may signal via alpha neurexins and possibly other receptors. |
| Gene ID | 11247 |
|---|---|
| Other Names | NPH4; NXPH4_HUMAN; NXPH4; NXPH4_RAT; neurexophilin 4 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | NXPH4 |
|---|---|
| Synonyms | NPH4 |
| Function | May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors. |
| Cellular Location | Secreted. |
| Tissue Location | Expressed in brain, spleen, and testis. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP99026
