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PCTAIRE2 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q00537 |
| Other Accession | Q00537 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 59582 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human PCTAIRE2 |
| Epitope Specificity | 301-400/523 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. |
| SUBUNIT | Found in a complex containing CABLES1, CDK16 and TDRD7. Interacts with TDRD7 |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with cyclins to phosphorylate key substrates involved in cell cycle progression. Another family of proteins, Cdk inhibitors, also play a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Members of the Cdk family include Cdk2–Cdk8, PCTAIRE-1–3, PITALRE and PITSLRE. PCTAIRE-1, PCTAIRE-2 and PCTAIRE-3 comprise a subfamily of cdc2-related serine/threonine kinases. PCTAIRE-1, which is expressed primarily in mammalian brain, interacts with a variety of proteins and is thought to be part of a multiple signal transduction cascade. PCTAIRE-2, also expressed in brain, may be important in terminally differentiated neurons. |
| Gene ID | 5128 |
|---|---|
| Other Names | PCTAIRE2; PCTK2; CDK17_HUMAN; CDK17; Cell division protein kinase 17; PCTAIRE-motif protein kinase 2; Serine/threonine-protein kinase PCTAIRE-2; 2.7.11.22; cyclin dependent kinase 17; PCTAIRE protein kinase 2 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CDK17 |
|---|---|
| Synonyms | PCTAIRE2, PCTK2 |
| Function | May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity). |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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