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CNDP1 Rabbit pAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IHC-F, IF, E
Primary Accession Q96KN2
Other Accession Q96KN2
Host Rabbit
Clonality Polyclonal
Calculated MW 56692 Da
Physical State Liquid
Immunogen KLH conjugated synthetic peptide derived from human CNDP1
Epitope Specificity 301-400/507
Isotype IgG
Purity affinity purified by Protein A
Buffer 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SIMILARITY Belongs to the peptidase M20A family.
SUBUNIT Homodimer.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions CNDP1 (Carnosine dipeptidase 1) belongs to the M20 metalloprotease family and is expressed in the adult nervous central system. It catalyzes preferential hydrolysis of the beta-Ala-|-His dipeptide (carnosine), and also anserine, Xaa-|-His dipeptides and other dipeptides including homocarnosine.
Additional Information
Gene ID 84735
Other Names CN1; CPGL2; HsT2308; CNDP1_HUMAN; CNDP1; CNDP dipeptidase 1; Carnosine dipeptidase 1; Glutamate carboxypeptidase-like protein 2; Serum carnosinase; 3.4.13.20; carnosine dipeptidase 1 (metallopeptidase M20 family); carnosinase 1; beta-Ala-His dipeptidase
Dilution WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name CNDP1 (HGNC:20675)
Function Catalyzes the peptide bond hydrolysis in Xaa-His dipeptides, displaying the highest activity toward carnosine (beta-alanyl-L- histidine).
Cellular Location Secreted
Tissue Location Found in serum and adult nervous central system. Absent in serum from patients with homocarnosinosis
Research Areas
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