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Mitoferrin 2/SLC25A28 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q96A46 |
| Other Accession | Q96A46 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 39272 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human Mitoferrin 2 |
| Epitope Specificity | 271-364/364 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the mitochondrial carrier (TC 2.A.29) family. Contains 3 Solcar repeats. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Mitoferrin 2, also known as MRS3/4 (mitochondrial RNA-splicing protein 3/4 homolog), mitochondrial iron transporter 2, NPD016, MRS4L or SLC25A28 (solute carrier family 25 member 28), is a 364 amino acid multi-pass membrane protein of the mitochondrial inner membrane that mediates iron uptake. Mitoferrin 2 is thought to play a role in heme synthesis of hemoproteins and iron-sulfur cluster assembly. Ubiquitously expressed, Mitoferrin 2 is found at high levels in skeletal muscle, heart, placenta, kidney, lung, liver, brain and pancreas. Mitoferrin 2 is a member of the mitochondrial carrier family and undergoes alternative splicing events to produce four isoforms. Mitoferrin 2 contains three solcar repeats and is encoded by a gene that maps to human chromosome 10q24.2. |
| Gene ID | 81894 |
|---|---|
| Other Names | MFRN2; MRS3/4; MRS4L; NPD016; MFRN2_HUMAN; SLC25A28; Mitochondrial RNA-splicing protein 3/4 homolog (MRS3/4 | hMRS3/4); Mitochondrial iron transporter 2; Solute carrier family 25 member 28; MFRN2_MOUSE; Mitochondrial RNA-splicing protein 3/4 homolog (MRS3/4); B2RYH0_RAT; solute carrier family 25, member 28; solute carrier family 25 (mitochondrial iron transporter), member 28; mitoferrin 2 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SLC25A28 |
|---|---|
| Synonyms | MFRN2 |
| Function | Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. |
| Cellular Location | [Isoform 1]: Mitochondrion inner membrane; Multi-pass membrane protein |
| Tissue Location | Ubiquitous. Expressed in placenta, lung, kidney, pancreas, liver, brain, skeletal muscle and heart |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP99146
